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| Hugh Jackman | Logan/Wolverine |
| Patrick Stewart | Prof. Charles Xavier |
| Ian McKellen | Eric Lehnsherr/Magneto |
| Halle Berry | Ororo Munroe/Storm |
| Famke Janssen | Jean Grey/Phoenix |
| Anna Paquin | Marie/Rogue |
| Rebecca Romijn | Raven Darkholme/Mystique |
| Kelsey Grammer | Dr. Henry 'Hank' McCoy/Beast |
| Shawn Ashmore | Bobby Drake/Iceman |
| Ellen Page | Kitty Pryde/Shadowcat |
| Ben Foster | Warren Worthington III/Angel |
| Aaron Stanford | John Allerdyce/Pyro |
| Olivia Williams | Moira MacTaggart |
| Shohreh Aghdashloo | Dr. Kavita Rao |
| James Marsden | Scott Summers/Cyclops |
The discovery of a cure for mutations leads to a turning point for Mutants . They may now choose to give up their powers and become fully human or retain their uniqueness and remain isolated. War looms between the followers of Charles Xavier, who preaches tolerance, and those of Magneto, who advocates survival of the fittest.
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