|Christopher Plummer||Abraham Van Helsing|
|Jonny Lee Miller||Simon Sheppard|
|Justine Waddell||Mary Heller|
|Colleen Ann Fitzpatrick||Lucy Westerman|
|Sean Patrick Harris||Trick|
|Jeri Ryan||Valerie Sharpe|
Long ago, Abraham Van Helsing imprisoned the infamous Count Dracula within a vault inside Carfax Abbey. In the present day, Van Helsing relies on Dracula's immortal blood to remain alive. But then thieves breaks into the vault and steal the vampire's coffin, thinking it contains something valuable. Liberated from his prison, Dracula seizes the opportunity to escape, but Van Helsing sets out to banish him to the crypt once again.