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| Tricia O'Kelley | Sylvia |
| Patrick J. Adams | Byron |
| Ryan Devlin | Walt |
| Mark Harmon | Dale |
| Kaitlin Olson | Sherry |
| Alex Kapp Horner | Emily |
| Marin Hinkle | Jane |
| Jon Cryer | Charles |
| Jane Lynch | J.D. |
| Blair Underwood | Fitz |
| Brandon Barrera | Ernest |
| Enrico Colantoni | George |
| Amie Donegan | Mary |
| Timothy Dvorak | Jack |
| Lucas Fleischer | Arthur |
| David Giuntoli | James |
When Sylvia, a morning-show weather forecaster in Seattle, learns that her lover is cheating on her, she confronts the cad during the broadcast and loses her job. Now unemployed and homeless, Sylvia moves in with her brother and must learn how to cope with being 35-years-old, single, and famous for melting down on live television.
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