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| William Holden | Pike Bishop |
| Ernest Borgnine | Dutch Engstrom |
| Robert Ryan | Deke Thornton |
| Edmond O'Brien | Freddie Sykes |
| Warren Oates | Lyle Gorch |
| Jaime Sanchez | Angel |
| Ben Johnson | Tector Gorch |
| Emilio Fernández | Gen. Mapache |
| Strother Martin | Coffer |
| L.Q. Jones | T.C. |
| Albert Dekker | Pat Harrigan |
| Bo Hopkins | Crazy Lee |
| Dub Taylor | Rev. Wainscoat |
| Jorge Russek | Maj. Zamorra |
| Alfonso Arau | Lt. Herrera |
| Chano Urueta | Don Jose |
| Sonia Amelio | Teresa |
| Aurora Clavel | Aurora |
| Elsa Cardenas | Elsa |
| Fernando Wagner | Cmdr. Frederick Mohr |
| Paul Harper | Ross |
An outlaw and his gang, on the run from the Mexican Army and bounty hunters, plot to rob a United States Army train.
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