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| Kate Hudson | Caroline Ellis |
| Gena Rowlands | Violet Devereaux |
| John Hurt | Ben Devereaux |
| Peter Sarsgaard | Luke |
| Joy Bryant | Jill |
| Maxine Barnett | Mama Cynthia |
| Tom Uskali | Robertson Thorpe |
| Jen Apgar | Madeleine Thorpe |
| Forrest Landis | Martin Thorpe |
| Jamie Lee Redmon | Redmon |
| Ronald McCall | Papa Justify |
| Jeryl Prescott Sales | Mama Cecile |
| Isaach De Bankolé | Creole Gas Station Owner |
| Andreas Beckett | Ballroom Dancer |
| Ann Dalrymple | Older Nurse |
| Justin Groetsch | Club Goer |
| David Jensen | Country doctor |
| Mark Krasnoff | Taxi/Truck Driver |
| Natalie McNeil | Cigar Smokin' Party Guest |
A woman takes a job as a hospice nurse for a couple who live in a New Orleans house with a troublesome history.
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