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| Amber Tamblyn | Tabitha "Tibby" Tomko-Rollins |
| Alexis Bledel | Lena Kaligaris |
| America Ferrera | Carmen Lowell |
| Blake Lively | Bridget |
| Jenna Boyd | Bailey Graffman |
| Bradley Whitford | Al |
| Nancy Travis | Lydia Rodman |
| Rachel Ticotin | Carmen's Mother |
| Mike Vogel | Eric Richman |
| Michael Rady | Kostas |
| Leonardo Nam | Brian |
| Maria Konstandarou | Yia Yia |
| George Touliatos | Papou |
| Kyle Schmid | Paul Rodman |
| Emily Tennant | Krista Rodman |
| Jacqueline Stewart | Lena's Mother |
| Sarah-Jane Redmond | Tibby's Mother |
| Ernie Lively | Bridget's Father |
| Kendall Cross | Bridget's Mother |
| Kristie Marsden | Olivia |
| Patricia Mayan Salazar | Camp Director Donna |
| Patricia Drake | Coach Karen |
| Valerie Tian | Interview Girl #1 |
| Georgia Craig | Saleslady |
| Erica Hubbard | Diana |
Four teenage friends keep in touch during their summer apart by passing along a cherished pair of blue jeans.
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