|John Hawkes||Mark O'Brien|
|William H. Macy||Father Brendan|
|W. Earl Brown||Rod|
Though a childhood bout with polio left him dependent on an iron lung, Mark O'Brien maintains a career as a journalist and poet. A writing assignment dealing with sex and the disabled piques Mark's curiosity, and he decides to investigate the possibility of experiencing sex himself. When his overtures toward a caregiver scare her away, he books an appointment with sex surrogate Cheryl Cohen Green to lose his virginity.