| Daniel Day-Lewis | Hawkeye/Nathaniel Poe |
| Madeleine Stowe | Cora Munro |
| Russell Means | Chingachgook |
| Eric Schweig | Uncas |
| Jodhi May | Alice Munro |
| Steven Waddington | Maj. Duncan Heyward |
| Wes Studi | Magua |
| Maurice Roëves | |
| Patrice Chéreau | Gen Montcalm |
Colonial guide Hawkeye, with his Indian friends, Chingachgook and Uncas, rescue British sisters from the Huron to take them to their father, the commander of Fort William Henry.
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