| Mark Wahlberg | Elliot Moore |
| Zooey Deschanel | Alma Moore |
| John Leguizamo | Julian |
| Betty Buckley | Mrs. Jones |
| Ashlyn Sanchez | Jess |
| Spencer Breslin | Josh |
| Robert Bailey Jr. | Jared |
| Frank Collison | Nursey Owner |
| Jeremy Strong | Private Auster |
| Alan Ruck | Principal |
| M. Night Shyamalan | Joey |
| Victoria Clark | Nursery Owner's Wife |
| Derege Harding | Train Conductor |
| Robert Lenzi | Jake |
An apocalyptic threat to humanity arrives out of the clear blue sky with a series of violent, inexplicable deaths spreading across the country. The cause of the terrifying phenomenon remains unknown, prompting science teacher Elliot Moore, his wife Alma and his colleague Julian to try to elude the invisible killer in Pennsylvania's farmland. Soon it becomes clear that no one is safe.
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