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| Woody Harrelson | One Eyed Jack Faro |
| David Cross | Larry Schwartzman |
| Dennis Farina | L.B.J. Deuce Fairbanks |
| Cheryl Hines | Lainie Schwartzman |
| Chris Parnell | Harold Melvin |
| Julie Claire | Dr. Jamie Sellers |
| Shannon Elizabeth | Toni |
| Mike Epps | Reggie Marshall |
| Judy Greer | Sharon Andrews |
| Estelle Harris | Ruth 'Nana' Melvin |
| Werner Herzog | The German |
| Gabe Kaplan | Seth Schwartzman |
Jack Faro is the grandson of a casino legend and a former poker champ himself, until he lost it all, including the casino he inherited, to liquor and alimony. In order to win back his casino, Jack must enter the upcoming World Championship of Poker, where he will face stiff competition from famous players like Deuce Fairbanks and Lainie Schwartzman .
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