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| Al Hedison | Andre Delambre |
| Patricia Owens | Helene Delambre |
| Vincent Price | François Delambre |
| Herbert Marshall | Insp. Charas |
| Kathleen Freeman | Emma (Delambre maid) |
| Betty Lou Gerson | Nurse Andersone |
| Charles Herbert | Philippe Delambre |
| Eugene Borden | Dr. Ejoute (uncredited) |
| Torben Meyer | Gaston (uncredited) |
| Harry Carter | Orderly (uncredited) |
| Charles Tannen | Doctor (uncredited) |
| Franz Roehn | Police doctor (uncredited) |
| Arthur Dulac | French waiter (uncredited) |
When scientist Andre Delambre tests his matter transporter on himself, an errant housefly makes its way into the transportation chamber, and things go horribly wrong. As a result, Delambre's head and arm are now that of the insect. Slowly losing himself to the fly, Delambre turns to his wife, Helene, for help. But when tragedy strikes, Delambre's brother and Inspector Charas are forced to pick up the investigation.
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