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| Sandra Bullock | Leigh Anne Tuohy |
| Tim McGraw | Sean Tuohy |
| Quinton Aaron | Michael Oher |
| Jae Head | S.J. |
| Lily Collins | Collins |
| Ray McKinnon | Coach Cotton |
| Kim Dickens | Mrs. Boswell |
| Adriane Lenox | Denise Oher |
| Kathy Bates | Miss Sue |
| Catherine Dyer | Mrs. Smith |
| Andy Stahl | Principal Sandstrom |
| Tom Nowicki | Literature Teacher |
| Libby Whittemore | Sarcastic Teacher |
| Brian Hollan | Jay Collis |
| Melody Weintraub | History Teacher |
| Sharon Morris | Investigator Granger |
| Omar Dorsey | ``Big Tony'' Hamilton |
| Paul Amadi | Steve Hamilton |
| Irone Singleton | Alton |
A homeless black teenager, Michael Oher has drifted in and out of the school system for years. Then Leigh Anne Tuohy and her husband, Sean, take him in, transforming Michael's life and theirs. With help from his new-found family, tutors and coaches, he realizes his potential as a student and football player.
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