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| Ryan Reynolds | George Lutz |
| Melissa George | Kathy Lutz |
| Jesse James | Billy Lutz |
| Jimmy Bennett | Michael Lutz |
| Chloe Moretz | Chelsea Lutz |
| Rachel Nichols | Lisa |
| Philip Baker Hall | Father McNamara |
| Isabel Conner | Jodie Defeo |
| Brendan Donaldson | Ronald Defeo |
| Annabel Armour | Realtor |
| Rich Komenich | Chief of Police |
| David Gee | ER Doctor |
| Danny McCarthy | Officer Greguski |
| Nancy Lollar | Librarian |
| José Taitano | Stitch |
| Jason Padgett | Charlie |
Strange events take place after a family moves into a new house that was the site of several gruesome murders.
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