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| Basil Rathbone | |
| Nigel Bruce | |
| Ida Lupino | |
| Alan Marshal | |
| Terry Kilburn | |
| George Zucco | |
| E.E. Clive | |
| Mary Gordon |
Sherlock Holmes and Dr. Watson square off against their archenemy, Professor Moriarty, who has designs on the Tower of London's Crown Jewels. As a perfect distraction from Moriarty's schemes, Holmes and Watson are contacted by a woman who claims that her family is in danger after her brother receives the same warning message her father got 10 years ago -- just before he was brutally murdered.
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