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| Melvin Van Peebles | Sweetback |
| Simon Chuckster | Beetle |
| Hubert Scales | Mu-Mu |
| John Dullaghan | Commissioner |
| West Gale | |
| Niva Rochelle | |
| Rhetta Hughes | Old Girl Friend |
| Nick Ferrari | |
| Ed Rue | |
| John Amos | Biker |
| Lavelle Roby | |
| Ted Hayden | |
| Mario Van Peebles | Young Sweetback / Kid |
| Sonja Dunson | |
| Michael Agustus | |
| Peter Russell | |
| Norman Fields | |
| Ron Prince | |
| Steve Cole | |
| Megan Van Peebles | Kid |
| Joe Tornatore | |
| Mike Angel | |
| Jeff Goodman | |
| Curt Matson | |
| Marria Evonee | |
| Jon Jacobs | |
| Bill Kirschner | |
| Vincent Barbi | |
| Chet Norris | |
| Joni Watkins |
A black man flees to Mexico after killing two white policemen who beat a black militant.
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