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| Norma Shearer | Nina Leeds Evans |
| Clark Gable | Dr. Ned Darrell |
| Alexander Kirkland | Sam 'Sammy' Evans |
| May Robson | Mrs. Evans |
| Maureen O'Sullivan | Madeline Arnold |
| Robert Young | Gordon Evans as a Young Man |
| Ralph Morgan | Charlie Marsden |
| Henry B. Walthall | Professor Leeds |
| Mary Alden | Mary, Leeds' Maid |
Nina Leeds loses the love of her life when he is killed in World War I. She marries the loyal Sam Evans, but immediately stops caring for him when she realizes that they cannot have children together. She eventually begins an extramarital romance with a doctor named Ned Darrell, and they have a child, Gordon . The domineering Nina attempts to pass the child off as Sam's own, leading to years of tragic family dysfunction.
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