| Robert Redford | Nathan Muir |
| Brad Pitt | Tom Bishop |
| Catherine McCormack | Elizabeth Hadley |
| Stephen Dillane | Charles Harker |
| Larry Bryggman | Troy Folger |
| Michael Paul Chan | Vincent Vy Ngo |
| Marianne Jean-Baptiste | Gladys Jennip |
| Ken Leung | Li |
| David Hemmings | Harry Duncan |
| Matthew Marsh | Dr. Byars |
| Todd Boyce | Robert Aiken |
| Amidou | Dr. Ahmed, the sheik's doctor |
| Charlotte Rampling | Anna Cathcart |
Redford stars as CIA operative Nathan Muir, who is on the brink of retirement from the field, when he learns his protégé Tom Bishop has been arrested in China on a charge of espionage. No stranger to the machinations of the CIA's top echelon, Muir hones all his skills and irreverent manner in order to find a way to free Bishop.
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