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| Jennifer Aniston | Renee Fitzpatrick |
| Maxine Bahns | Hope Fitzpatrick |
| Edward Burns | Mickey Fitzpatrick |
| Cameron Diaz | Heather Davis |
| John Mahoney | Mr. Fitzpatrick |
| Mike McGlone | Francis Fitzpatrick |
| Amanda Peet | Molly |
| Frank Vincent | Ron |
| Anita Gillette | Carol |
| Leslie Mann | Connie |
| Robert Weil | Mr. De Lucca |
The lives -- and relationships -- of married brothers Mickey and Francis Fitzpatrick are disrupted by the presence of Heather, Mickey's ex-girlfriend. Heather has just reentered Mickey's life, but at the same time she's sleeping with Francis. Romantic entanglements, marital woes, and sibling rivalries result ... and teach the brothers Fitzpatrick a few things about the game of life.
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