| Will Smith | Oscar |
| Robert De Niro | Don Lino |
| Renée Zellweger | Angie |
| Jack Black | Lenny |
| Angelina Jolie | Lola |
| Martin Scorsese | Sykes |
| Peter Falk | Don Brizzi |
| Michael Imperioli | Frankie |
| Vincent Pastore | Luca |
| Doug E. Doug | Bernie |
| Ziggy Marley | Ernie |
| Katie Couric | Katie Current |
| James Madio | Vinny |
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Underachiever Oscar is a pint-sized fish with grand aspirations. When mob-connected great white shark Frankie is accidentally killed, Oscar concocts a story with Frankie's peace-loving brother Lenny that it was he who murdered the shark. Suddenly hailed ''Sharkslayer'' by his aquatic brethren, Oscar has bigger fish to fry when Frankie's father, mob boss Don Lino, dispatches his henchmen to track down his son's killer.
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