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| Mia Farrow | Rosemary Woodhouse |
| John Cassavetes | Guy Woodhouse |
| Ruth Gordon | Minnie Castevet |
| Sidney Blackmer | Roman Castevet |
| Maurice Evans | Edward "Hutch" Hutchins |
| Ralph Bellamy | Dr. Abe Sapirstein |
| Elisha Cook Jr. | Mr. Nicklas |
| Patsy Kelly | Laura-Louise McBirney |
| Charles Grodin | Dr. C.C. Hill |
A young wife comes to believe that her offspring is not of this world. Waifish Rosemary Woodhouse and her struggling actor husband Guy move to a New York City apartment building with an ominous reputation and odd neighbors Roman and Minnie Castavet . When Rosemary becomes pregnant she becomes increasingly isolated, and the diabolical truth is revealed only after Rosemary gives birth.
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