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| Robert Downey Jr. | |
| Sam Neill | |
| David Thewlis | |
| Polly Walker | |
| Meg Ryan | |
| Ian McKellen | |
| Hugh Grant | |
| Hugh McDiarmid | |
| Mary MacLeod | |
| Mark Letheren |
In order to keep one of his mistresses, Celia, at arm's length, King Charles II asks the royal physician, Robert Merivel, to marry her under the proviso that they never become intimate. Merivel agrees, only to discover he can't resist Celia, and soon finds himself out of the king's favor. Destitute, he devotes himself to helping Londoners suffering from the plague, and in the process falls in love with an equally poor woman, Katherine .
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