|Anthony Stewart Head||Nathan/Repo Man|
|Alexa Vega||Shilo Wallace|
|Paul Sorvino||Rotti Largo|
|Bill Moseley||Luigi Largo|
|Sarah Brightman||Blind Mag|
In the mid-21st century, an epidemic of organ failures leads to the rise of GeneCo., a company providing transplants at a great price. Those who miss their payments become targets of GeneCo. mercenaries, who repossess the organs. In a world of drug addiction and legalized murder, a sheltered youth seeks a cure for her rare disease as well as information about her family's mysterious history. Her questions are answered at ``The Genetic Opera.''