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| Andy Lawrence | T.J. Detweiler |
| Rickey D'Shon Collins | Vince Lasalle |
| Pamela Segall | Ashley Spinelli |
| Jason Davis | Mikey Blumberg |
| Ashley Johnson | Gretchen Grundler |
| Courtland Mead | Gustavus 'Gus' P. Griswald |
| April Winchell | Ms. Finster/Mrs. Detweiler |
| Dabney Coleman | Principal Vance Prickly |
| Robert Goulet | Mikey's Singing Voice |
| Melissa Joan Hart | Becky |
| Peter MacNicol | Fenwick |
| James Woods | Benedict |
| Diedrich Bader | Guard #2 |
| Allyce Beasley | Miss Grotke |
| Gregg Berger | Tech #1 |
| Klee Bragger | Digger Sam |
| Clancy Brown | Bald Guy |
| Dan Castellaneta | Guard #1 |
| Toran Caudell | King Bob |
| Rachel Crane | Ashley Q |
| E.G. Daily | Cap'n Sticky |
| Lee Ermey | Colonel O'Malley |
| Ron Glass | Dr. Lazenby / Tech #2 |
| Tony Jay | Dr. Rosenthal |
| Clyde Kusatsu | Mr. Yamashiro |
| Charles Kimbrough | Mort Chalk |
| Tress MacNeille | Ms. Lemon / Lunchlady Irma / Opera Director / Dr. Steinheimer |
| Andrea Martin | Lunchlady Harriet |
| Anndi McAfee | Ashley A |
| Mark Robert Myers | Technician |
A group of children tries to save summer vacation after their former principal plans to create a permanent winter.
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