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| Robert De Niro | Jake La Motta |
| Cathy Moriarty | Vickie La Motta |
| Joe Pesci | Joey La Motta |
| Frank Vincent | Salvy |
| Nicholas Colasanto | Tommy Como |
| Theresa Saldana | Lenore |
| Frank Adonis | Patsy |
| Mario Gallo | Mario |
| Frank Topham | Toppy |
| Lori Anne Flax | Irma |
| Joseph Bono | Guido |
| James V. Christy | Dr. Pinto |
| Bernie Allen | Comedian |
The violent nature of prizefighter Jake LaMotta leads first to a boxing championship, then to a downward spiral of self-destruction.
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