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| Meryl Streep | Suzanne Vale |
| Shirley MacLaine | Doris Mann |
| Dennis Quaid | Jack Faulkner |
| Gene Hackman | Lowell Kolchek |
| Richard Dreyfuss | Doctor Frankenthal |
| Rob Reiner | Joe Pierce |
| Mary Wickes | Grandma |
| Conrad Bain | Grandpa |
| Annette Bening | Evelyn Ames |
| Simon Callow | Simon Asquith |
| Gary Morton | Marty Wiener |
| Dana Ivey | Wardrobe Mistress |
Hollywood actress Suzanne Vale is on a slippery slope as a recovering addict. On exit from rehab, it is recommended she stay with her mother, who has become a somewhat champion drinker herself. Suzanne therefore struggles to maintain her sobriety and her sanity in the company of Doris.
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