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| Irene Dunne | Julie Gardiner Adams |
| Cary Grant | Roger Adams |
| Beulah Bondi | Miss Oliver |
| Edgar Buchanan | Applejack Carney |
| Ann Doran | Dotty ``Dot'' |
| Eva Lee Kuney | Trina (Age 6) |
| Leonard Willey | Doctor Hartley |
| Wallis Clark | Judge |
| Walter Soderling | Billings |
| Baby Biffle | Trina (Age 1) |
| Edmund Elton | Minister (uncredited) |
| Billy Bevan | McDougal (uncredited) |
A woman contemplating divorce from her husband recalls their early years together and the tragedies that ensued.
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