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| Michelle Pfeiffer | Melanie Parker |
| George Clooney | Jack Taylor |
| Mae Whitman | Maggie Taylor |
| Alex D. Linz | Sammy Parker |
| Charles Durning | Lew |
| Jon Robin Baitz | Mr. Yates, Jr. |
| Ellen Greene | Mrs. Elaine Lieberman |
| Joe Grifasi | Manny Feldstein |
| Pete Hamill | Frank Burroughs |
| Anna Maria Horsford | Evelyn |
| Gregory Jbara | Freddy |
| Sheila Kelley | Kristen |
| Barry Kivel | Mr. Yates, Sr. |
| Robert Klein | Dr. Martin |
| George Martin | Mr. Smith Leland |
| Michael Massee | Eddie Parker |
| Amanda Peet | Celia |
| Bitty Schram | Marla |
| Holland Taylor | Rita |
| Rachel York | Liza |
On a hectic day, architect Melanie, single mom of a small boy, meets news columnist Jack, divorced dad of a little girl .
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