|Laurence Fishburne||20/20 Mike|
|Dominic Chianese Jr.||Freddie Nine Lives|
|Paul Calderone||Manny Rivera|
|Michael Paul Chan||Buddha|
|Andres ``Dres'' Titus||Hector|
A gritty drama centered around brotherhood and friendship, ``Once in the Life'' is a realistic depiction of how everyday choices affect our path in life. It is a cautionary tale about making the wrong choices and the inevitable, tragic conclusion of an individual who is drawn to a life of crime - - once in the life, always in the life.