|Lon Chaney Jr.||Lennie|
|Noah Beery Jr.||Whit|
|Barbara Pepper||Girl (uncredited)|
|Henriette Kay||Girl (uncredited)|
|Eddie Dunn||Bus Driver (uncredited)|
In this acclaimed adaptation of the novella by John Steinbeck, migrant farmhands George Milton and Lennie Small begin working at a ranch near Soledad, California, after the mentally handicapped Lennie got the pair in trouble at their last job. George dreams of settling down on their own farm where Lennie can tend his beloved rabbits, but despite George's best efforts to protect his friend, events accidentally take a tragic turn.