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| Walter Huston | |
| James Stewart | |
| Beulah Bondi | |
| Gene Reynolds | |
| Guy Kibbee | |
| Charles Coburn | |
| John Carradine | |
| Ann Rutherford |
When preacher Ethan Wilkins relocates to a small, hardscrabble town on the Ohio River, he's surprised by the poor treatment he gets from the locals, but bears it quietly. His son, Jason, however, hates the town. Against his father's wishes, he aspires to be a doctor, and demands that his mother sell off her few possessions to pay for his education. When the Civil War breaks out, he finds success as a surgeon, but is estranged from his family.
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