| Cary Grant | T.R. Devlin |
| Ingrid Bergman | Alicia Huberman |
| Claude Rains | Alex Sebastian |
| Louis Calhern | Captain Paul Prescott |
| Leopoldine Konstantin | Madame Anna Sebastian |
| Reinhold Schunzel | Dr. Anderson |
| Moroni Olsen | Walter Beardsley |
In order to help bring Nazis to justice, U.S. government agent T.R. Devlin recruits Alicia Huberman, the American daughter of a convicted German war criminal, as a spy. As they begin to fall for one another, Alicia is instructed to win the affections of Alexander Sebastian, a Nazi hiding out in Brazil. When Sebastian becomes serious about his relationship with Alicia, the stakes get higher, and Devlin must watch her slip further undercover.
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