|Ashley Olsen||Jane Ryan|
|Mary-Kate Olsen||Roxy Ryan|
|Eugene Levy||Max Lomax|
|Dr. Drew Pinsky||Dr. Ryan|
|Darrell Hammond||Hudson McGill|
|Andrea Martin||Senator Anne Lipton|
|Mary Bond Davis||Big Shirl|
Jane and Roxy Ryan are teenage Long Island twins who find themselves on numerous misadventures when they trek into Manhattan on a school day. While the studious Jane intends to give an important speech in hopes of winning a scholarship, the more relaxed and carefree Roxy wants to track down her favorite New York City rock group. Trailing behind them, however, is Max Lomax, their school's obsessive truant officer.