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| Rosalind Russell | Ruth Sherwood |
| Brian Aherne | Robert Baker |
| Janet Blair | Eileen Sherwood |
| George Tobias | Appopolous |
| Allyn Joslyn | Chic Clark |
| Elizabeth Patterson | Grandma Sherwood |
| Grant Mitchell | Walter Sherwood |
| Richard Quine | Frank Lippincott |
| June Havoc | Effie Shelton |
| Donald MacBride | Officer Lonigan |
| Gordon Jones | ''The Wreck'' Loomis |
| Jeff Donnell | Helen Loomis |
| Clyde Fillmore | Ralph Craven |
| Minna Phillips | Mrs. Wade |
When starry-eyed sisters, Ruth and Eileen Sherwood, make the leap from rural Idaho to downtown New York City, they believe they are going to make their fortunes. However, upon arriving, they find the Big Apple a little less glamorous than had they expected. After moving into a trashy basement apartment in Greenwich Village, the sisters eventually make the acquaintance of hotshot magazine editor Robert Baker, who vows to help them both succeed.
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