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| Bela Lugosi | Dr. Mirakle |
| Sidney Fox | Mlle. Camille L'Espanaye |
| Leon Waycoff | Pierre Dupin |
| Bert Roach | Paul |
| Brandon Hurst | Prefect of Police |
| Noble Johnson | Janos The Black One, Mirakle's Black Servant |
| D'Arcy Corrigan | Morgue Keeper |
| Arlene Francis | Woman of the Streets, Mirakle Victim |
| Herman Bing | Franz Odenheimer (uncredited) |
In 1845 Paris, mysterious Dr. Mirakle demonstrates his theories on evolution using his ape, Erik, at a carnival visited by medical student Pierre Dupin and his girlfriend, Camille Espanaye . Unknown to his audience, Mirakle performs experiments in his secret laboratory that involve mixing human blood with that of Erik's. After three prostitutes are found dead from being injected with a strange substance, Pierre is alarmed when Camille goes missing.
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