| Anna Friel | Marina |
| Michelle Williams | Holly |
| Kyle MacLachlan | Daniel |
| Oliver Milburn | Nat |
| Trudie Styler | Linda |
| Marianne Denicourt | Isabel |
| Nicky Henson | Ray |
| Allan Corduner | Max |
| Deborah Findlay | Judith |
| Steve John Shepherd | Carl |
Two best friends in London grow up, attend college and maintain their relationship for three decades.
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