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| Hugh Laurie | Sam Bell |
| Joely Richardson | Lucy Bell |
| Adrian Lester | George |
| James Purefoy | Carl Phipps |
| Tom Hollander | Ewan Proclaimer |
| Joanna Lumley | Sheila |
| Rowan Atkinson | Mr. James |
| Dawn French | Charlene |
| Emma Thompson | Druscilla |
| Rachael Stirling | Joanna |
| Matthew MacFadyen | |
| Anna Lindgren | Make-up Artist (uncredited) |
| Kelly Reilly | Nimnh |
| Stephen Simms | Trevor |
| Yasmin Bannerman | Melinda |
An upwardly mobile Briton with writer's block and his wife try desperately to conceive a child.
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