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| Piper Perabo | Pauline Oster |
| Jessica Paré | Victoria Moller |
| Mischa Barton | Mary Bradford |
| Jackie Burroughs | Fay Vaughn |
| Graham Greene | Joe Menzies |
| Mimi Kuzyk | Eleanor Bannet |
| Luke Kirby | Jake |
| Grace Kung | Lauren |
| Emily Vancamp | Allison Moller |
``Lost and Delirious'' is about the friendship of three teenagers and how they experience it in a private school. Throughout the film, the lost girls question their relationships with one another and the authority of others while desperately attempting to seek out true love.
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