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| Brad Pitt | Tristan Ludlow |
| Anthony Hopkins | Col. William Ludlow |
| Aidan Quinn | Alfred Ludlow |
| Julia Ormond | Susannah Fincannon Ludlow |
| Henry Thomas | Samuel Ludlow |
| Karina Lombard | Isabel Decker Ludlow (a.k.a. Isabel Two) |
| Gordon Tootoosis | One Stab |
| Tantoo Cardinal | Pet |
| Paul Desmond | Decker |
| Christina Pickles | Isabel Ludlow |
| Robert Wisden | John T. O'Banion |
| John Novak | James O'Banion |
| Kenneth Welsh | Sheriff Tynert |
| Bill Dow | Longley |
| Sam Sarkar | Rodriguez |
| Nigel Bennett | Asgaard |
| Keegan Macintosh | Boy Tristan |
| Eric Johnson | Teen Tristan |
A retired cavalry officer and his sons live on a pre-World War I Montana cattle ranch.
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