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| Harrison Ford | Detective Joe Gavilan |
| Josh Hartnett | Detective K.C. Calden |
| Lena Olin | Ruby |
| Bruce Greenwood | Bennie Macko |
| Isaiah Washington | Sartain |
| Lolita Davidovich | Cleo |
| Keith David | Leon |
| Master P | Julius Armas |
| Gladys Knight | Olivia Robidoux |
| Lou Diamond Phillips | Wanda |
| Meredith Scott Lynn | I.A. Detective Jackson |
| Tom Todoroff | I.A. Detective Zino |
| James MacDonald | Danny Broome |
| Kurupt | K-Ro |
| André Benjamin | Silk Brown |
| Alan Dale | Commander Preston |
| Clyde Kusatsu | Coroner Chung |
| Dwight Yoakam | Leroy Wasley |
| Martin Landau | Wasley |
| Eric Idle | Celebrity |
| Frank Sinatra Jr. | Marty Wheeler |
| Robert Wagner | Himself |
| Johnny Grant | Himself |
| Smokey Robinson | Cabbie |
A veteran Los Angeles detective and his partner investigate the slaying of a rap group.
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