| Luke Wilson | Henry Poole |
| Radha Mitchell | Dawn |
| Adriana Barraza | Esperanza |
| George Lopez | Father Salazar |
| Cheryl Hines | Meg |
| Richard Benjamin | Dr. Fancher |
| Morgan Lily | Millie |
| Rachel Seiferth | Patience |
| Beth Grant | Josie |
A community of believers demonstrates the power of faith for a man who is dying.
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