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| Nicolas Cage | Randall "Memphis" Raines |
| Angelina Jolie | Sara "Sway" Wayland |
| Giovanni Ribisi | Kip Raines |
| Delroy Lindo | Detective Roland Castlebeck |
| Will Patton | Atley Jackson |
| Christopher Eccleston | Raymond Calitri |
| Chi McBride | Donny Astricky |
| Robert Duvall | Otto Halliwell |
| Scott Caan | Tumbler |
| Timothy Olyphant | Detective Drycoff |
| William Lee Scott | Toby |
| Vinnie Jones | The Sphinx |
| James Duval | Freb |
| TJ Cross | Mirror Man |
| Frances Fisher | Junie Halliwell |
| Grace Zabriskie | Helen Raines |
| Jaime Bergman | blonde in drag race |
| Holiday Hopke | waitress |
| Harry Van Gorkum | Forge |
| Mike Owen | Kid in Rice Burner |
| Grace Una | Jenny |
| Jesse Corti | Officer Axton |
| Stephen Shellen | Roger the car salesman |
| Alexandra Balahoutis | DMV clerk |
| Rainbow Borden | Carjacker No. 1 |
| Victor Manni | worker |
| Sanjay Pandya | Glass House Guy |
| Doria Anselmo | Glass House Girl |
| Lois Hall | old woman |
| Dean Rader-Duval | Hype |
A former thief must agree to steal 50 cars in one night to save his brother from being killed by a vehicle smuggler.
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