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| Winona Ryder | Susanna Kaysen |
| Angelina Jolie | Lisa |
| Clea DuVall | Georgina |
| Brittany Murphy | Daisy |
| Elizabeth Moss | Polly |
| Jared Leto | Tobias Jacobs |
| Jeffrey Tambor | Dr. Potts |
| Vanessa Redgrave | Dr. Wick |
| Whoopi Goldberg | Valerie |
| Mary Kay Place | Barbara Gilcrest |
| Jillian Armenante | Cynthia |
| Steve Altes | Medic |
| Angela Bettis | Janet |
| John Bobby | Therapist #2 (uncredited) |
| Travis Fine | Nurse John |
Set in the changing world of the late 1960s, ``Girl, Interrupted'' is the searing true story of Susanna Kaysen, a young woman who finds herself at a renowned mental institution for troubled young women, where she must choose between the world of people who belong on the inside-like the seductive and dangerous Lisa -- or the often difficult world of reality on the outside.
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