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| Ethan Hawke | Vincent Freeman |
| Uma Thurman | Irene Cassini |
| Jude Law | Jerome Eugene Morrow |
| Gore Vidal | Director Josef |
| Alan Arkin | Det. Hugo |
| Loren Dean | Anton Freeman |
| Jayne Brook | Marie Freeman |
| Elias Koteas | Antonio Freeman |
| Chad Christ | Vincent Freeman - Teen |
| William Lee Scott | Young Anton |
| Tony Shalhoub | German |
| Ernest Borgnine | Caesar |
An outcast takes part in a complicated and perilous scheme to assume the identity of a genetically engineered citizen .
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