|Bill Nighy||Leonard Saber|
|Zach Galifianakis||Ben Kendall|
|Will Arnett||Special Agent Kip Killian|
|Gabriel Casseus||Agent Carter|
|Jack Conley||Agent Trigstad|
|Tyler Patrick Jones||Connor|
|Loudon Wainwright III||Grandpa Goodman|
Armed with the latest high-tech spy gear, a guinea pig named Darwin and his team of specially trained rodents are often the last line of defense against chaos and destruction. But when the government shuts them down and ships them off to a pet shop, Darwin and his gang will have to find a way to break out and prevent a mad billionaire from taking over the world.