| David Duchovny | Gus |
| Nicky Katt | Hitler |
| Catherine Keener | Lee |
| Mary McCormack | Linda |
| David Hyde Pierce | Carl |
| Julia Roberts | Francesca/Catherine |
| Blair Underwood | Calvin/Nicholas |
| Brad Pitt | Brad / Himself |
| David Fincher | Film Director |
A film-within-a-film evolves as the lives of several people unfold during one day in Los Angeles.
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