|Kelly Ripa||Nat's mom|
|Ed Begley Jr.||Poopchev|
|Adrienne Barbeau||Scooter's mom|
|Sandy Simpson||Commander Armstrong|
|Eddie Frierson||Commander Aldrin|
|David Cowgill||Commander Collins|
|Mimi Maynard||IQ's mom|
Nat the fly loves listening to his grandfather tell stories of adventures from his youth. Desperate to experience some derring-do of his own, Nat convinces two of his friends to stow away on Apollo 11. The high-flying trio have the adventure of a lifetime when they must prevent a Russian bug from sabotaging the mission.