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| Hugh Jackman | Roddy |
| Kate Winslet | Rita |
| Jean Reno | Le Frog |
| Bill Nighy | Whitey |
| Andy Serkis | Spike |
| Shane Richie | Syd |
| Ian McKellen | Toad |
| Kathy Burke | Rita's Mum |
| David Suchet | Rita's Dad |
| Miriam Margolyes | Rita's Grandma |
| Geoffrey Palmer | Gilbert |
After an ignoble landing in Ratropolis, a pampered rodent enlists the help of a sewer scavenger in finding his way back to his posh London flat. Getting home is not the only problem, however; a rodent-hating toad wants his notorious cousin, Le Frog, to exterminate the pair.
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