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| Robert De Niro | Walt Koontz |
| Philip Seymour Hoffman | Rusty Zimmerman |
| Barry Miller | Leonard Wilcox |
| Chris Bauer | Jacko |
| Skipp Sudduth | Tommy Walsh |
| Wilson Jermaine Heredia | Cha-Cha |
| Nashom Benjamin | Amazing Grace |
| Scott Allen Cooper | Ivana |
| Rory Cochrane | Pogo |
| Daphne Rubin-Vega | Tia |
| Wanda De Jesus | Karen |
| Karina Arroyave | Amber Garcia Sanchez |
| John Enos | Sonny |
| Jude Ciccolella | Detective Noonan |
| Mina Bern | Mrs. Spivak |
| Vincent Laresca | Raymond Camacho |
| Madhur Jaffrey | Dr. Nirmala |
| Mark Margolis | Vinnie |
| Shiek Mahmud-Bey | Vance |
| Luis Saguar | Mr. Z |
| Kyle Rivers | LeShaun |
| Sammy Rhee | Mr. Pim |
| Hyunsoo Lee | Mrs. Pim |
| Richie LaMontagne | Carmine |
| Penny Balfour | Cristal |
| Winter B. Uhlarik | Tasha |
| Raven O | Notorious F.A.G. |
| Joey Arias | Stormy |
| Jackie Beat | Gypsy |
| Blake Willett | Cop |
After a debilitating stroke and on his doctor's advice, a conservative man takes singing lessons from a drag-queen neighbor .
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