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| Kiefer Sutherland | Nelson |
| Julia Roberts | Rachel Mannus |
| Kevin Bacon | David Labraccio |
| William Baldwin | Joe Hurley |
| Oliver Platt | Randy Steckle |
| Kimberly Scott | Winnie Hicks |
| Joshua Rudoy | Billy Mahoney |
Seeking answers about the afterlife, Chicago medical student Nelson persuades his fellow pupils to help him end his life, and then resuscitate him in the nick of time. Atheist David, playboy Joe and troubled Rachel also journey into the unknown, looking for meaning in their own lives. As the experiments become more perilous, each is forced to contend with the paranormal consequences of trespassing on the other side.
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