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| Kenan Thompson | Fat Albert |
| Kyla Pratt | Doris |
| Shedrack Anderson III | Rudy |
| Jermaine Williams | Mush Mouth |
| Keith Robinson | Bill |
| Alphonso McAuley | Bucky |
| Aaron Frazier | Weird Harold |
| Marques B. Houston | |
| Dania Ramirez | Lauri |
| Omari Grandberry | Reggie |
| J. Mack Slaughter Jr. | Arthur |
| Bill Cosby | Himself |
| Jeremy Suarez | Russell |
| Raven-Symone | Danielle |
A lonely teen's tears create a portal through which the 1970s cartoon character and his pals emerge into flesh-and-blood reality.
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